hmm... masalahnya gw baca di forum anime di luar negeri tuh, ada chapter yang ga ditayangin di komiknya, chapter 110
Di chapter tersebut diceritakan kalau di misa mati bunuh diri
According to How to Read 13, Misa loses her memories related to using the Death Note and retains her love for Light. Since it is in the nature of a Death Note user to "suffer misfortune", Misa falls into despair after someone "like Matsuda" "probably let it slip" that Light died.[10]
Misa commits suicide one year later on February 14, 2011. The cloaked woman who appears at the end of the manga is not Misa, she is an unnamed follower of Kira. Misa's fate is not shown in the manga at all; she was last seen staying at the Teito Hotel. Ohba stated that this was simply because he did not have a situation to fit her in.[10]
Info from:
http://en.wikipedia.org/wiki/Misa_Amane